Eledoisin Related Peptide ( Eledoisin-Related Peptide; Eledoisin RP )

Catalog No. M29877 CAS No. 2990-43-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Eledoisin Related Peptide
Note

Research use only, not for human use.
Brief Description

Eledoisin Related Peptide is a tachykinin receptor ligand and analogue of substance P. ERP can increase spontaneous activity and depolarizing neurons by decreasing membrane conductance.
Description

Eledoisin Related Peptide is a tachykinin receptor ligand and analogue of substance P. ERP can increase spontaneous activity and depolarizing neurons by decreasing membrane conductance. (In Vivo):Eledoisin Related Peptide shares with Substance P (SP) a common N-terminal amino acid sequence and has been shown by to have SP-like activity in the periphery (gut and salivary glands) and the CNS. Eledoisin-related peptide seems to be roughly equipotent with Substance P at identical ejection currents on the single-cell activity of neurons in this nucleus. Both glutamate and substance P (and its analogue, eledoisin-related peptide) have excitatory effects on the activity of respiratory neurons and reflex interneurons.
Synonyms

Eledoisin-Related Peptide; Eledoisin RP
Pathway

GPCR/G Protein
Target

Neurokinin Receptor
Recptor

Tachykinin receptor
Research Area

——
Indication

——

Severini C, et al. The tachykinin peptide family. Pharmacol Rev. 2002 Jun;54(2):285-322.

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